Pesquisa | Portal de Pesquisa da BVS

1.

Macrophage P2Y6 receptor deletion attenuates atherosclerosis by limiting foam cell formation through phospholipase Cß/store-operated calcium entry/calreticulin/scavenger receptor A pathways.

Li, Yehong; Zhou, Mengze; Li, Huanqiu; Dai, Chen; Yin, Li; Liu, Chunxiao; Li, Yuxin; Zhang, Enming; Dong, Xinli; Ji, Hui; Hu, Qinghua.

Eur Heart J ; 45(4): 268-283, 2024 Jan 27.

Artigo em Inglês | MEDLINE | ID: mdl-38036416

2.

Thiamine analogues featuring amino-oxetanes as potent and selective inhibitors of pyruvate dehydrogenase.

Chan, Alex H Y; Ho, Terence C S; Leeper, Finian J.

Bioorg Med Chem Lett ; 98: 129571, 2024 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-38036274

3.

Open-chain thiamine analogues as potent inhibitors of thiamine pyrophosphate (TPP)-dependent enzymes.

Chan, Alex H Y; Ho, Terence C S; Leeper, Finian J.

Org Biomol Chem ; 21(32): 6531-6536, 2023 08 16.

Artigo em Inglês | MEDLINE | ID: mdl-37522836

4.

Synthesis of pyrrothiamine, a novel thiamine analogue, and evaluation of derivatives as potent and selective inhibitors of pyruvate dehydrogenase.

Chan, Alex H Y; Ho, Terence C S; Agyei-Owusu, Kwasi; Leeper, Finian J.

Org Biomol Chem ; 20(45): 8855-8858, 2022 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-36326656

5.

The effects of thiamine pyrophosphate on propofol-induced oxidative liver injury and effect on dysfunction.

Acun Delen, Leman; Korkmaz Disli, Zeliha; Tas, Hakan G; Kuyrukluyildiz, Ufuk; Yazici, Gulce N; Süleyman, Bahadir; Kuzucu, Mehmet; Gürsu, Cebrail; Suleyman, Halis.

Gen Physiol Biophys ; 41(1): 63-70, 2022 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-35253651

6.

Regulation of Malate Dehydrogenases and Glutamate Dehydrogenase of Mammalian Brain by Thiamine in vitro and in vivo.

Mezhenska, O A; Aleshin, V A; Kaehne, T; Artiukhov, A V; Bunik, V I.

Biochemistry (Mosc) ; 85(1): 27-39, 2020 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-32079515

7.

Otoprotective Effect of Cortexin, Cogitum, and Elkar Administered Simultaneously with Netromycin in the Experiment.

D'yakonova, I N; Ishanova, Yu S; Rakhmanova, I V.

Bull Exp Biol Med ; 169(4): 458-462, 2020 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-32894392

8.

Ca²⁺-dependent inhibition of branched-chain α-ketoacid dehydrogenase kinase by thiamine pyrophosphate.

Noguchi, Seisuke; Kondo, Yusuke; Ito, Rina; Katayama, Takahiro; Kazama, Shunsuke; Kadota, Yoshihiro; Kitaura, Yasuyuki; Harris, Robert A; Shimomura, Yoshiharu.

Biochem Biophys Res Commun ; 504(4): 916-920, 2018 10 12.

Artigo em Inglês | MEDLINE | ID: mdl-30224059

9.

Overexpression of plastid transketolase in tobacco results in a thiamine auxotrophic phenotype.

Khozaei, Mahdi; Fisk, Stuart; Lawson, Tracy; Gibon, Yves; Sulpice, Ronan; Stitt, Mark; Lefebvre, Stephane C; Raines, Christine A.

Plant Cell ; 27(2): 432-47, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25670766

10.

Ronald Breslow (1931-2017).

Cornish, Virginia W.

Nature ; 552(7684): 176, 2017 12 14.

Artigo em Inglês | MEDLINE | ID: mdl-29239359

11.

Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels.

Vignisse, Julie; Sambon, Margaux; Gorlova, Anna; Pavlov, Dmitrii; Caron, Nicolas; Malgrange, Brigitte; Shevtsova, Elena; Svistunov, Andrey; Anthony, Daniel C; Markova, Natalyia; Bazhenova, Natalyia; Coumans, Bernard; Lakaye, Bernard; Wins, Pierre; Strekalova, Tatyana; Bettendorff, Lucien.

Mol Cell Neurosci ; 82: 126-136, 2017 07.

Artigo em Inglês | MEDLINE | ID: mdl-28506637

12.

The Protective Effect of Thiamine Pryophosphate Against Sugar-Induced Retinal Neovascularisation in Rats.

Cinici, Emine; Mammadov, Renad; Findik, Huseyin; Suleyman, Bahadir; Cetin, Nihal; Calik, Ilknur; Balta, Hilal; Hakki Tas, Ismail; Sener, Ebru; Altuner, Durdu.

Int J Vitam Nutr Res ; 88(3-4): 137-143, 2018 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-31165688

13.

Structural basis for the magnesium-dependent activation of transketolase from Chlamydomonas reinhardtii.

Pasquini, Miriam; Fermani, Simona; Tedesco, Daniele; Sciabolini, Chiara; Crozet, Pierre; Naldi, Marina; Henri, Julien; Vothknecht, Ute; Bertucci, Carlo; Lemaire, Stéphane D; Zaffagnini, Mirko; Francia, Francesco.

Biochim Biophys Acta Gen Subj ; 1861(8): 2132-2145, 2017 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-28552632

14.

The effect of thiamine pyrophosphate on ethambutol-induced ocular toxicity.

Cinici, Emine; Cetin, Nihal; Ahiskali, Ibrahim; Suleyman, Bahadir; Altuner, Durdu; Alp, Hamit Hakan; Sener, Ebru; Calik, Ilknur; Suleyman, Halis.

Cutan Ocul Toxicol ; 35(3): 222-7, 2016 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-26339826

15.

The design, synthesis and biological evaluation of novel thiamin diphosphate analog inhibitors against the pyruvate dehydrogenase multienzyme complex E1 from Escherichia coli.

Feng, Lingling; He, Junbo; He, Haifeng; Zhao, Lulu; Deng, Lingfu; Zhang, Li; Zhang, Lin; Ren, Yanliang; Wan, Jian; He, Hongwu.

Org Biomol Chem ; 12(44): 8911-8, 2014 Nov 28.

Artigo em Inglês | MEDLINE | ID: mdl-25268578

16.

The protective effect of thiamine pyrophosphate, but not thiamine, against cardiotoxicity induced with cisplatin in rats.

Coskun, Resit; Turan, Mehmet Ibrahim; Turan, Isil Siltelioglu; Gulapoglu, Mine.

Drug Chem Toxicol ; 37(3): 290-4, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24215635

17.

Probing riboswitch-ligand interactions using thiamine pyrophosphate analogues.

Chen, Liuhong; Cressina, Elena; Dixon, Neil; Erixon, Karl; Agyei-Owusu, Kwasi; Micklefield, Jason; Smith, Alison G; Abell, Chris; Leeper, Finian J.

Org Biomol Chem ; 10(30): 5924-31, 2012 Aug 14.

Artigo em Inglês | MEDLINE | ID: mdl-22514012

18.

Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch.

Serganov, Alexander; Polonskaia, Anna; Phan, Anh Tuân; Breaker, Ronald R; Patel, Dinshaw J.

Nature ; 441(7097): 1167-71, 2006 Jun 29.

Artigo em Inglês | MEDLINE | ID: mdl-16728979

19.

Biochemically and histopathologically comparative review of thiamine's and thiamine pyrophosphate's oxidative stress effects generated with methotrexate in rat liver.

Demiryilmaz, Ismail; Sener, Ebru; Cetin, Nihal; Altuner, Durdu; Suleyman, Bahadir; Albayrak, Fatih; Akcay, Fatih; Suleyman, Halis.

Med Sci Monit ; 18(12): BR475-81, 2012 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-23197226

20.

[Drug with a high metabolic activity, cocarnit, in the treatment of diabetic cardiac autonomic neuropathy].

Popov, S V; Melekhovets', O K; Demikhova, N V; Vynnychenko, L B.

Lik Sprava ; (3-4): 75-81, 2012.

Artigo em Ucraniano | MEDLINE | ID: mdl-23356142

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